Gulati A, Choudhuri R, Gupta A, Singh S, Ali SKN, Sidhu GK, Haque PD, Rahate P, Bothra AR, Singh GP, Maheshwari S, Jeswani D, Haveri S, Agarwal A, Agrawal NR. A Multicentric, Randomized, Controlled Phase III Study of Centhaquine (Lyfaquin®) as a Resuscitative Agent in Hypovolemic Shock Patients. Drugs. 2021 Jun;81(9):1079-1100. doi: 10.1007/s40265-021-01547-5. Epub 2021 Jun 1. PMID: 34061314; PMCID: PMC8167383. Link to Article Link to FULL FREE PDF
Gulati A, Jain D, Agrawal NR, Rahate P, Choudhuri R, Das S, Dhibar DP, Prabhu M, Haveri S, Agarwal R, Lavhale MS. Resuscitative Effect of Centhaquine (Lyfaquin®) in Hypovolemic Shock Patients: A Randomized, Multicentric, Controlled Trial. Adv Ther. 2021 Jun;38(6):3223-3265. doi: 10.1007/s12325-021-01760-4. Epub 2021 May 10. PMID: 33970455; PMCID: PMC8189997. Link to Article Link to FULL FREE PDF
Geevarghese M 3rd, Patel K, Gulati A, Ranjan AK. Role of adrenergic receptors in shock. Front Physiol. 2023 Jan 16;14:1094591. doi: 10.3389/fphys.2023.1094591. PMID: 36726848; PMCID: PMC9885157. Link to Article Link to FULL FREE PDF
Khanna A, Vaidya K, Shah D, Ranjan AK, Gulati A. Centhaquine Increases Stroke Volume and Cardiac Output in Patients with Hypovolemic Shock. J Clin Med. 2024 Jun 27;13(13):3765. doi: 10.3390/jcm13133765. PMID: 38999331; PMCID: PMC11242165. Link to Article Link to FULL FREE PDF
Ranjan AK, Zhang Z, Briyal S, Gulati A. Centhaquine Restores Renal Blood Flow and Protects Tissue Damage After Hemorrhagic Shock and Renal Ischemia. Front Pharmacol. 2021 May 3;12:616253. doi: 10.3389/fphar.2021.616253. PMID: 34012389; PMCID: PMC8126696. Link to Article Link to FULL FREE PDF
Ranjan AK, Gulati A. Controls of Central and Peripheral Blood Pressure and Hemorrhagic/Hypovolemic Shock. J Clin Med. 2023 Jan 31;12(3):1108. doi: 10.3390/jcm12031108. PMID: 36769755; PMCID: PMC9917827. Link to Article Link to FULL FREE PDF
Chalkias A, Pais G, Gulati A. Effect of Centhaquine on the Coagulation Cascade in Normal State and Uncontrolled Hemorrhage: A Multiphase Study Combining Ex Vivo and In Vivo Experiments in Different Species. Int J Mol Sci. 2024 Mar 20;25(6):3494. doi: 10.3390/ijms25063494. PMID: 38542464; PMCID: PMC10970680. Link to Article Link to FULL FREE PDF
Augoustides JG. Emerging Therapeutics in Hypovolemic Shock With Centhaquine Citrate-A Novel Venopressor That Leverages the Alpha Receptor Family. J Cardiothorac Vasc Anesth. 2025 Jun 1:S1053-0770(25)00450-1. doi: 10.1053/j.jvca.2025.05.056. Epub ahead of print. PMID: 40562673. Link to Article Link to FULL FREE PDF
Legrand M, Ranjan A, Rammohan S, De Backer D, Ostermann M, Gulati A, Vincent JL, Khanna AK. Therapeutic Potential of Centhaquine Citrate, a Selective Alpha-2B Adrenoceptor Agonist, in the Management of Circulatory Shock. Drugs. 2025 Jun;85(6):777-799. doi: 10.1007/s40265-025-02176-y. Epub 2025 Apr 20. PMID: 40253656; PMCID: PMC12098521. Link to Article Link to FULL FREE PDF