The IV Fluid Guide: 0.9% NaCl, Ringers Lactate, Plasmalyte & Albumin

This page is a work in progress as a IV Fluid guide and will continue to grow throughout the years. Last updated on 3/3/22. This page is quite the mess right now if I am being honest. I will get it together at some point. Just many projects running simultaneously. Table of Contents for the …

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Vitamin D for COVID-19: Are we missing a potential therapeutic?

Allow me to start off with a disclaimer. I favor cheap and readily available therapies over expensive therapeutics. There has been a lot of talk about Vitamin D and it's relationship with COVID-19. Honestly too much for me to get into. It seems as if there's something new every day. What we lack, though, is …

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icu nutrition

Nutrition in the Critically Ill/Intensive Care Unit (ICU)

In this post which will be updated continuously, I will be examining the clinical questions regarding ICU nutrition. These data do not apply to the non-ICU patients. The first thing that we need to acknowledge is that nutrition in the critically ill is not one size fits all nor set it and forget it in …

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Phosphorus/Hypophosphatemia in the Critically Ill: Let’s Correct it!

I covered this topic about hypophosphatemia in the critically ill back in the infancy of my Instagram account on 4/19/2019. Seems like an eternity ago. I know it's not very Zentensivist of me to have this as part of my practice, but this is something I actively chase in my patients. Phosphorus, generally speaking, is …

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covid precautions

Discontinuing Contact Precautions in COVID-19 Patients

We've gotten quite good at putting today negative pressure rooms for our patients who are hospitalized with COVID. We've gotten our PPE sorted out. We're pretty solid with our donning and doffing. But when should we discontinue contact precautions on these patients? Should they be on isolation for their entire hospitalization? When can family members …

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Remdesivir: $3120 worth of “uncertain clinical importance”

Here's my bias on 8/22/2020. I don't think that Remdesivir is a game-changer by any stretch of the imagination. This is subject to change with future studies. I could be wrong. To me, it is a pharmacologic agent looking for an indication. Gilead has spent $2.45 million dollars lobbying (per NPR) Congress in the first …

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zinc metabolic resuscitation

Zinc for Metabolic Resuscitation in Critical Illness

Did you know that zinc is the second-most abundant trace metal in the human body? A quick reminder that iron comes in first place. Zinc is an essential component of protein structure and function. It enables gene transcription and is a "catalytic component of approximately 2000 enzymes" (Read, et al). Could we use zinc for …

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Hydroxychloroquine (HCQ) for Postexposure Prophylaxis in COVID-19

I wish this was a positive study regarding hydroxychloroquine (HCQ) for postexposure prophylaxis but unfortunately it is not. Let's start off with a bit of a head scratcher. I'm struggling with how they worded the study "Postexposure prophylaxis". Prophylaxis, by definition, means "action taken to prevent disease" per the Oxford dictionary. But if you are …

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Vitamin C for COVID: Possible Prophylaxis & Adjunctive Therapy

Bias alert. I am bullish on Vitamin C. Aren't things easier when you don't have to wonder these things? I digress. The article cited for this post was published in the journal Nutrition on 7/25/2020. Obviously, the title of the paper "Vitamin C as prophylaxis and adjunctive medical treatment for COVID-19?" caught my attention. Hat …

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