IV Vitamin C in Sepsis: It Should Decrease Vasopressor Dose & Duration

On By eddyjoemdIn Metabolic Resuscitation, Sepsis and Septic Shock

The VITAMINS trial looking at IV Vitamin C didn’t pan out was not a positive study as it was conducted. It was surprising as intravenous (IV) Vitamin C in sepsis should help decrease vasopressor dose and duration. My contention with that study is that they took too long to initiate the study drug. A median …

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Melatonin for Sepsis: The potential benefits to improve outcomes

On By eddyjoemdIn Metabolic Resuscitation, Sepsis and Septic Shock

You’re following along on my page bc you know I’m trying to find the most cutting-edge treatments and therapies for my critically ill patients. I hope to keep on pumping out eye catching content such as this article on melatonin for sepsis. Please share with you’re nerdy friends who would also find this nerdy content …

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VITAMINS Trial: Timing was delayed to administer the “vitamins”

On By eddyjoemdIn Metabolic Resuscitation, Sepsis and Septic Shock

You all know my bias. It shouldn't be a surprise given my body of work: I wanted the VITAMINS Trial to be a positive study. I wanted patients to benefit from this therapy and SURVIVE. I cannot understand the vitriol I have received in my direct messages when I shared my initial take on the …

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Dopamine for Cardiogenic Shock: Shown to Increase Mortality.

On By eddyjoemdIn Vasopressors & Inotropes

Does your friendly neighborhood cardiologist or intensivist start your Cardiogenic Shock patient on dopamine? Do you ever ask them when was the last time they read a study? I don’t mean to be harsh but this data is now almost a decade old. This study placed dopamine far down on the vasopressor selection totem pole. …

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methylene blue septic shock

Methylene Blue in Sepsis & Septic Shock

On By eddyjoemdIn Sepsis and Septic Shock, Vasopressors & Inotropes

I don’t know about you all, but I’m constantly working on finding new ways to treat my septic shock patients who, based on the numbers from more extensive studies, have a mortality rate between 25-35%. I have used methylene blue occasionally for post-CPB vasoplegia, but would it work in septic shock? UPDATE: This page was …

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Vitamin D Supplementation in Critically Ill ICU Patients

On By eddyjoemdIn ICU Pearls, Metabolic Resuscitation

I am constantly reading and educating myself in an attempt to gain whatever edge I possibly can for my patients. Their survival and quality of life is what I have personally dedicated my life to. Being someone who is following along on my journey, I can safely assume you're doing the same. I have become …

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Pre-oxygenation: High flow nasal cannula vs. BVM

On By eddyjoemdIn Airway Management, NIV: HFNC & BiPAP

A sentinel event is one where, amongst other different outcomes, leads to death. In critical care, anesthesia, and emergency medicine, we often deal with emergent airways on patients who are on the brink of death unless we intervene expediently. Despite having performed many intubations in my young career, I have the utmost respect for every …

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