Cytokines tend to break things in critical illness.
Pro-inflammatory cytokines cause vasodilation.
Anti-inflammatory cytokines cause immunosupression.
Inventing a way to get rid of those cytokines sounds like a good idea, right?
Cytosorb has been on out the market and trialed in sepsis, ARDS, cardiac surgery or recovery after cardiac arrest in the ICU.
It sounds expensive, but does it work?
A systematic review and meta-analysis was published in May of 2023 analyzing if Cytosorb is helpful.
Hat tip to the authors. Read these data for yourself as I personally have zero experience with Cytosorb.
Was there a mortality benefit? Nope.
Was there a benefit to ICU or Hospital length of stay? Nope.
The authors also looked at vasopressors and other biomarkers with no clear benefit to our patients.
At least there weren’t any significant adverse effects.
Should we start using this type of technology in our ICU?
It sure doesn’t seem like it.
Do you have any experience using Cytosorb?
CLICK HERE to learn how I care for my patients after cardiac surgery.
Citations for Cytosorb
Becker S, Lang H, Vollmer Barbosa C, Tian Z, Melk A, Schmidt BMW. Efficacy of CytoSorb®: a systematic review and meta-analysis. Crit Care. 2023 May 31;27(1):215. doi: 10.1186/s13054-023-04492-9. PMID: 37259160.
Link to Article
Link to FULL FREE PDF
Consider purchasing my book, ‘The Vasopressor & Inotrope Handbook’!
I have written “The Vasopressor & Inotrope Handbook: A Practical Guide for Healthcare Professionals,” a must-read for anyone caring for critically ill patients (check out the reviews)! You have several options to get a physical copy. If you’re in the US, you can order A SIGNED & PERSONALIZED COPY for $29.99 or via AMAZON for $32.99 (for orders in or outside the US).
Ebook versions are available via AMAZON KINDLE for $9.99, APPLE BOOKS, and GOOGLE PLAY.
¡Excelentes noticias! Mi libro ha sido traducido al español y está disponible a traves de AMAZON. Las versiones electrónicas están disponibles para su compra for solo $9.99 en AMAZON KINDLE, APPLE BOOKS y GOOGLE PLAY.
When you use these affiliate links, I earn an additional commission at no extra cost to you, which is a great way to support my work.
Disclaimer
Although great care has been taken to ensure that the information in this post is accurate, eddyjoe, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom.