Midodrine Citations: The Vasopressor & Inotrope Handbook

Steinbach K, Weidinger P. Der Einflubb von Midodrin auf die Orthostase [Effect of midodrin on orthostasis]. Wien Klin Wochenschr. 1973 Sep 21;85(38):621-4. German. PMID: 4148067.

Schramek G, Wolkerstorfer H. Zur Therapie der konstitutionellen Hypotonie. Erfahrungen mit Midodrin [Therapy of constitutional hypotension. Experiences with midodrin]. Wien Med Wochenschr. 1973 Sep 29;123(39):571-3. German. PMID: 4748156.

Sharma S, Bhambi B. Successful treatment of hypotension associated with stunned myocardium with oral midodrine therapy. J Cardiovasc Pharmacol Ther. 2005 Mar;10(1):77-9. doi: 10.1177/107424840501000109. PMID: 15821841.
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Levine AR, Meyer MJ, Bittner EA, Berg S, Kalman R, Stanislaus AB, Ryan C, Ball SA, Eikermann M. Oral midodrine treatment accelerates the liberation of intensive care unit patients from intravenous vasopressor infusions. J Crit Care. 2013 Oct;28(5):756-62. doi: 10.1016/j.jcrc.2013.05.021. Epub 2013 Jul 8. PMID: 23845791.
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Whitson MR, Mo E, Nabi T, Healy L, Koenig S, Narasimhan M, Mayo PH. Feasibility, Utility, and Safety of Midodrine During Recovery Phase From Septic Shock. Chest. 2016 Jun;149(6):1380-3. doi: 10.1016/j.chest.2016.02.657. Epub 2016 Mar 4. PMID: 26953217.
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Rizvi MS, Trivedi V, Nasim F, Lin E, Kashyap R, Andrijasevic N, Gajic O. Trends in Use of Midodrine in the ICU: A Single-Center Retrospective Case Series. Crit Care Med. 2018 Jul;46(7):e628-e633. doi: 10.1097/CCM.0000000000003121. PMID: 29613861.
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Hammond DA, Smith MN, Peksa GD, Trivedi AP, Balk RA, Menich BE. Midodrine as an Adjuvant to Intravenous Vasopressor Agents in Adults With Resolving Shock: Systematic Review and Meta-Analysis. J Intensive Care Med. 2020 Nov;35(11):1209-1215. doi: 10.1177/0885066619843279. Epub 2019 Apr 28. PMID: 31030630.
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Tchen S, Sullivan JB. Clinical utility of midodrine and methylene blue as catecholamine-sparing agents in intensive care unit patients with shock. J Crit Care. 2020 Jun;57:148-156. doi: 10.1016/j.jcrc.2020.02.011. Epub 2020 Feb 19. PMID: 32145658.
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Costa-Pinto R, Yong ZT, Yanase F, Young C, Brown A, Udy A, Young PJ, Eastwood G, Bellomo R. A pilot, feasibility, randomised controlled trial of midodrine as adjunctive vasopressor for low-dose vasopressor-dependent hypotension in intensive care patients: The MAVERIC study. J Crit Care. 2022 Feb;67:166-171. doi: 10.1016/j.jcrc.2021.11.004. Epub 2021 Nov 18. PMID: 34801917.
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Tremblay JA, Laramée P, Lamarche Y, Denault A, Beaubien-Souligny W, Frenette AJ, Kontar L, Serri K, Charbonney E. Potential risks in using midodrine for persistent hypotension after cardiac surgery: a comparative cohort study. Ann Intensive Care. 2020 Sep 14;10(1):121. doi: 10.1186/s13613-020-00737-w. PMID: 32926256; PMCID: PMC7490305.
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Angeli P, Volpin R, Gerunda G, Craighero R, Roner P, Merenda R, Amodio P, Sticca A, Caregaro L, Maffei-Faccioli A, Gatta A. Reversal of type 1 hepatorenal syndrome with the administration of midodrine and octreotide. Hepatology. 1999 Jun;29(6):1690-7. doi: 10.1002/hep.510290629. PMID: 10347109.
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Prakash S, Garg AX, Heidenheim AP, House AA. Midodrine appears to be safe and effective for dialysis-induced hypotension: a systematic review. Nephrol Dial Transplant. 2004 Oct;19(10):2553-8. doi: 10.1093/ndt/gfh420. Epub 2004 Jul 27. PMID: 15280522.
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Sharma S, Lardizabal JA, Bhambi B. Oral midodrine is effective for the treatment of hypotension associated with carotid artery stenting. J Cardiovasc Pharmacol Ther. 2008 Jun;13(2):94-7. doi: 10.1177/1074248408317709. PMID: 18495904.
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Kalambokis G, Fotopoulos A, Economou M, Pappas K, Tsianos EV. Effects of a 7-day treatment with midodrine in non-azotemic cirrhotic patients with and without ascites. J Hepatol. 2007 Feb;46(2):213-21. doi: 10.1016/j.jhep.2006.09.012. Epub 2006 Nov 10. PMID: 17156883.
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Poveromo LB, Michalets EL, Sutherland SE. Midodrine for the weaning of vasopressor infusions. J Clin Pharm Ther. 2016 Jun;41(3):260-5. doi: 10.1111/jcpt.12375. Epub 2016 Mar 4. PMID: 26945564.
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Safety of Oral Midodrine as a Method of Weaning From Intravenous Vasoactive Medication in the Medical Intensive Care Unit
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Hammond DA, Smith MN, Meena N. Considerations on Midodrine Use in Resolving Septic Shock. Chest. 2016 Jun;149(6):1582-3. doi: 10.1016/j.chest.2016.03.054. PMID: 27287581.
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Macielak SA, Vollmer NJ, Haddad NA, Nabzdyk CGS, Nei SD. Hemodynamic Effects of an Increased Midodrine Dosing Frequency. Crit Care Explor. 2021 Apr 26;3(4):e0405. doi: 10.1097/CCE.0000000000000405. PMID: 33912835; PMCID: PMC8078337.
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Reed BN, Gale SE, Ramani G. Continuation of Newly Initiated Midodrine Therapy: Appropriate in Patients With Heart Failure? Crit Care Med. 2019 Oct;47(10):e845. doi: 10.1097/CCM.0000000000003914. PMID: 31524705.
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Zakir RM, Folefack A, Saric M, Berkowitz RL. The use of midodrine in patients with advanced heart failure. Congest Heart Fail. 2009 May-Jun;15(3):108-11. doi: 10.1111/j.1751-7133.2008.00042.x. PMID: 19522958.
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Jensen BC, O’Connell TD, Simpson PC. Alpha-1-adrenergic receptors: targets for agonist drugs to treat heart failure. J Mol Cell Cardiol. 2011 Oct;51(4):518-28. doi: 10.1016/j.yjmcc.2010.11.014. Epub 2010 Nov 28. PMID: 21118696; PMCID: PMC3085055.
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Nagendran M, Russell JA, Walley KR, Brett SJ, Perkins GD, Hajjar L, Mason AJ, Ashby D, Gordon AC. Vasopressin in septic shock: an individual patient data meta-analysis of randomised controlled trials. Intensive Care Med. 2019 Jun;45(6):844-855. doi: 10.1007/s00134-019-05620-2. Epub 2019 May 6. PMID: 31062052.
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Turner DW, Attridge RL, Hughes DW. Vasopressin Associated With an Increase in Return of Spontaneous Circulation in Acidotic Cardiopulmonary Arrest Patients. Ann Pharmacother. 2014 Aug;48(8):986-991. doi: 10.1177/1060028014537037. Epub 2014 May 28. PMID: 24871568.
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