Peripheral Vasopressors: The Vasopressor & Inotrope Handbook

The following are the citations used for my book “The Vasopressor & Inotrope Handbook: A Practical Guide for Healthcare Professionals.” If you stumbled onto this page via a search engine, you have several options to get a physical copy. If you’re in the US, you can order A SIGNED & PERSONALIZED COPY for $29.99 or via AMAZON (for orders outside the US). Ebook versions: AMAZON KINDLE for $9.99. APPLE BOOKS and GOOGLE PLAY. Mi libro ha sido traducido al español y las versiones electrónicas están disponibles para su compra for solo $9.99 en AMAZON KINDLE, APPLE BOOKS y GOOGLE PLAY. When you use these affiliate links, I earn an additional commission at no extra cost to you, which is a great way to support my work.

  1. Datar S, Gutierrez E, Schertz A, Vachharajani V. Safety of Phenylephrine Infusion Through Peripheral Intravenous Catheter in the Neurological Intensive Care Unit. J Intensive Care Med. 2018 Oct;33(10):589-592. doi: 10.1177/0885066617712214. Epub 2017 Jun 1. PMID: 28569131.
    Link to NOT FREE Article
  2. Permpikul C, Tongyoo S, Viarasilpa T, Trainarongsakul T, Chakorn T, Udompanturak S. Early Use of Norepinephrine in Septic Shock Resuscitation (CENSER). A Randomized Trial. Am J Respir Crit Care Med. 2019 May 1;199(9):1097-1105. doi: 10.1164/rccm.201806-1034OC. PMID: 30704260.
    Link to Article
    Link to FULL FREE PDF
  3. Ospina-Tascón GA, Hernandez G, Alvarez I, Calderón-Tapia LE, Manzano-Nunez R, Sánchez-Ortiz AI, Quiñones E, Ruiz-Yucuma JE, Aldana JL, Teboul JL, Cavalcanti AB, De Backer D, Bakker J. Effects of very early start of norepinephrine in patients with septic shock: a propensity score-based analysis. Crit Care. 2020 Feb 14;24(1):52. doi: 10.1186/s13054-020-2756-3. PMID: 32059682; PMCID: PMC7023737.
    Link to Article
    Link to FULL FREE PDF
  4. McGee DC, Gould MK. Preventing complications of central venous catheterization. N Engl J Med. 2003 Mar 20;348(12):1123-33. doi: 10.1056/NEJMra011883. PMID: 12646670.
    Link to Article AND FULL FREE PDF
  5. Parienti JJ, Mongardon N, Mégarbane B, Mira JP, Kalfon P, Gros A, Marqué S, Thuong M, Pottier V, Ramakers M, Savary B, Seguin A, Valette X, Terzi N, Sauneuf B, Cattoir V, Mermel LA, du Cheyron D; 3SITES Study Group. Intravascular Complications of Central Venous Catheterization by Insertion Site. N Engl J Med. 2015 Sep 24;373(13):1220-9. doi: 10.1056/NEJMoa1500964. PMID: 26398070.
    Link to Article AND FULL FREE PDF
  6. Owen VS, Rosgen BK, Cherak SJ, Ferland A, Stelfox HT, Fiest KM, Niven DJ. Adverse events associated with administration of vasopressor medications through a peripheral intravenous catheter: a systematic review and meta-analysis. Crit Care. 2021 Apr 16;25(1):146. doi: 10.1186/s13054-021-03553-1. PMID: 33863361; PMCID: PMC8050944.
    Link to Article
    Link to FULL FREE PDF
  7. Evans L, Rhodes A, Alhazzani W, Antonelli M, Coopersmith CM, French C, Machado FR, Mcintyre L, Ostermann M, Prescott HC, Schorr C, Simpson S, Wiersinga WJ, Alshamsi F, Angus DC, Arabi Y, Azevedo L, Beale R, Beilman G, Belley-Cote E, Burry L, Cecconi M, Centofanti J, Coz Yataco A, De Waele J, Dellinger RP, Doi K, Du B, Estenssoro E, Ferrer R, Gomersall C, Hodgson C, Møller MH, Iwashyna T, Jacob S, Kleinpell R, Klompas M, Koh Y, Kumar A, Kwizera A, Lobo S, Masur H, McGloughlin S, Mehta S, Mehta Y, Mer M, Nunnally M, Oczkowski S, Osborn T, Papathanassoglou E, Perner A, Puskarich M, Roberts J, Schweickert W, Seckel M, Sevransky J, Sprung CL, Welte T, Zimmerman J, Levy M. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Med. 2021 Nov;47(11):1181-1247. doi: 10.1007/s00134-021-06506-y. Epub 2021 Oct 2. PMID: 34599691; PMCID: PMC8486643.
    Link to Article
    Link to FULL FREE PDF
  8. Cardenas-Garcia J, Schaub KF, Belchikov YG, Narasimhan M, Koenig SJ, Mayo PH. Safety of peripheral intravenous administration of vasoactive medication. J Hosp Med. 2015 Sep;10(9):581-5. doi: 10.1002/jhm.2394. Epub 2015 May 26. PMID: 26014852.
    Link to (NOT FREE) Article
  9. Loubani OM, Green RS. A systematic review of extravasation and local tissue injury from administering vasopressors through peripheral intravenous and central venous catheters. J Crit Care. 2015 Jun;30(3):653.e9-17. doi: 10.1016/j.jcrc.2015.01.014. Epub 2015 Jan 22. PMID: 25669592.
    Link to (NOT FREE) Article
  10. Tian DH, Smyth C, Keijzers G, Macdonald SP, Peake S, Udy A, Delaney A. Safety of peripheral administration of vasopressor medications: A systematic review. Emerg Med Australas. 2020 Apr;32(2):220-227. doi: 10.1111/1742-6723.13406. Epub 2019 Nov 7. PMID: 31698544.
    Link to (NOT FREE) Article
  11. Lewis T, Merchan C, Altshuler D, Papadopoulos J. Safety of the Peripheral Administration of Vasopressor Agents. J Intensive Care Med. 2019 Jan;34(1):26-33. doi: 10.1177/0885066616686035. Epub 2017 Jan 11. PMID: 28073314.
    Link to (NOT FREE) Article
  12. Medlej K, Kazzi AA, El Hajj Chehade A, Saad Eldine M, Chami A, Bachir R, Zebian D, Abou Dagher G. Complications from Administration of Vasopressors Through Peripheral Venous Catheters: An Observational Study. J Emerg Med. 2018 Jan;54(1):47-53. doi: 10.1016/j.jemermed.2017.09.007. Epub 2017 Oct 27. PMID: 29110979.
    Link to Article
    Link to FULL FREE PDF
  13. Delgado T, Wolfe B, Davis G, Ansari S. Safety of peripheral administration of phenylephrine in a neurologic intensive care unit: A pilot study. J Crit Care. 2016 Aug;34:107-10. doi: 10.1016/j.jcrc.2016.04.004. Epub 2016 Apr 13. PMID: 27288620.
    Link to (NOT FREE) Article
  14. National Institutes of Health (NIH). Common Terminology Criteria for Adverse Events, V5.0. November 2017. Available at: https://ctep.cancer.gov/protocoldevelopment/electronic_applications/docs/ctcae_v5_quick_reference_8.5×11.pdf. Accessed September 5, 2023.
    Link to FULL FREE PDF
  15. EXTRAVASATION. Journal of Infusion Nursing 29(1):p S61-S62, January 2006.
    Link to (NOT FREE) Article
  16. Pancaro C, Shah N, Pasma W, Saager L, Cassidy R, van Klei W, Kooij F, Vittali D, Hollmann MW, Kheterpal S, Lirk P. Risk of Major Complications After Perioperative Norepinephrine Infusion Through Peripheral Intravenous Lines in a Multicenter Study. Anesth Analg. 2020 Oct;131(4):1060-1065. doi: 10.1213/ANE.0000000000004445. PMID: 32925324.
    Link to Article AND FULL FREE PDF
  17. LEVOPHED package insert, Lake Forest, IL: Hospira, Inc.; 2020.
    Link to Package Insert

    NEW FOR SECOND EDITION
  18. O’Grady NP. Prevention of Central Line-Associated Bloodstream Infections. N Engl J Med. 2023 Sep 21;389(12):1121-1131. doi: 10.1056/NEJMra2213296. PMID: 37733310.
    Link to (NOT FREE) Article
  19. Barbash IJ. Real World Data on Peripheral Vasopressors in Septic Shock. Chest. 2024 Apr;165(4):762-763. doi: 10.1016/j.chest.2023.11.005. PMID: 38599747.
    Link to Article
    Link to FULL FREE PDF
  20. Gandhi ZJ, Dugar S, Sato R. Do I always need a central venous catheter to administer vasopressors? Cleve Clin J Med. 2024 May 1;91(5):287-291. doi: 10.3949/ccjm.91a.23033. PMID: 38692697.
    Link to Article
    Link to FULL FREE PDF
  21. Hussain N, Jovaisa T, Puthucheary Z, Pearse R, Phull MK. Peripherally administered vasopressors in critically ill adult patients: A survey of UK healthcare professional practices, attitudes and experiences. J Intensive Care Soc. 2024 Jul 25;25(4):391-398. doi: 10.1177/17511437241259443. PMID: 39524075; PMCID: PMC11549726.
    Link to Article
    Link to FULL FREE PDF
  22. Jan KM, Ben-Jacob TK. Con: Central Lines Should Be the Preferred Method of Vasopressor Administration. J Cardiothorac Vasc Anesth. 2024 Jul 26:S1053-0770(24)00500-7. doi: 10.1053/j.jvca.2024.07.040. Epub ahead of print. PMID: 39155187.
    Link to (NOT FREE) Article
  23. Munroe ES, Heath ME, Eteer M, Gershengorn HB, Horowitz JK, Jones J, Kaatz S, Tamae Kakazu M, McLaughlin E, Flanders SA, Prescott HC. Use and Outcomes of Peripheral Vasopressors in Early Sepsis-Induced Hypotension Across Michigan Hospitals: A Retrospective Cohort Study. Chest. 2024 Apr;165(4):847-857. doi: 10.1016/j.chest.2023.10.027. Epub 2023 Oct 26. PMID: 37898185; PMCID: PMC11214906.
    Link to (NOT FREE) Article
  24. Munroe ES. A Case for the Evidence-Based Use of Peripheral Vasopressors. Chest. 2024 Feb;165(2):236-238. doi: 10.1016/j.chest.2023.09.015. PMID: 38336432.
    Link to Article
    Link to FULL FREE PDF
  25. Munroe ES, Weinstein J, Gershengorn HB, Karlic KJ, Seelye S, Sjoding MW, Valley TS, Prescott HC. Understanding How Clinicians Personalize Fluid and Vasopressor Decisions in Early Sepsis Management. JAMA Netw Open. 2024 Apr 1;7(4):e247480. doi: 10.1001/jamanetworkopen.2024.7480. PMID: 38639934; PMCID: PMC11031682.
    Link to Article and FULL FREE PDF
  26. Samara E, Tzimas PG, El Tahan MR. How to “Endgame” Safe Peripheral Vasopressor Administration. J Cardiothorac Vasc Anesth. 2024 Nov;38(11):2857-2858. doi: 10.1053/j.jvca.2024.04.004. Epub 2024 Apr 7. PMID: 38908929.
    Link to Article
    Link to FULL FREE PDF
  27. Takeshita J, Kawaguchi A, Kawasaki T, Ishihara T, Shime N. Local Adverse Events Associated with Peripheral Vasoactive Infusion in Children: A Systematic Review with Meta-analysis. J Cardiothorac Vasc Anesth. 2024 Dec;38(12):3215-3223. doi: 10.1053/j.jvca.2024.08.020. Epub 2024 Aug 13. PMID: 39227190.
    Link to (NOT FREE) Article
  28. Teja B, Bosch NA, Diep C, Pereira TV, Mauricio P, Sklar MC, Sankar A, Wijeysundera HC, Saskin R, Walkey A, Wijeysundera DN, Wunsch H. Complication Rates of Central Venous Catheters: A Systematic Review and Meta-Analysis. JAMA Intern Med. 2024 May 1;184(5):474-482. doi: 10.1001/jamainternmed.2023.8232. Erratum in: JAMA Intern Med. 2024 Jun 1;184(6):707. doi: 10.1001/jamainternmed.2024.2175. PMID: 38436976.
    Link to Article and FULL FREE PDF
  29. Yerke JR, Mireles-Cabodevila E, Chen AY, Bass SN, Reddy AJ, Bauer SR, Kokoczka L, Dugar S, Moghekar A. Peripheral Administration of Norepinephrine: A Prospective Observational Study. Chest. 2024 Feb;165(2):348-355. doi: 10.1016/j.chest.2023.08.019. Epub 2023 Aug 21. PMID: 37611862; PMCID: PMC10851275.
    Link to Article
    Link to FULL FREE PDF
  30. Gershengorn HB, Basu T, Horowitz JK, McLaughlin E, Munroe E, O’Malley M, Hsaiky L, Flanders SA, Bernstein SJ, Paje D, Chopra V, Prescott HC. The Association of Vasopressor Administration through a Midline Catheter with Catheter-related Complications. Ann Am Thorac Soc. 2023 Jul;20(7):1003-1011. doi: 10.1513/AnnalsATS.202209-814OC. PMID: 37166852.
    Link to Article
    Link to FULL FREE PDF
  31. Nguyen TT, Surrey A, Barmaan B, Miller S, Oswalt A, Evans D, Dhindsa H. Utilization and extravasation of peripheral norepinephrine in the emergency department. Am J Emerg Med. 2021 Jan;39:55-59. doi: 10.1016/j.ajem.2020.01.014. Epub 2020 Jan 8. PMID: 31959524.
    Link to (NOT FREE) Article
  32. Thomsen SL, Boa R, Vinter-Jensen L, Rasmussen BS. Safety and Efficacy of Midline vs Peripherally Inserted Central Catheters Among Adults Receiving IV Therapy: A Randomized Clinical Trial. JAMA Netw Open. 2024 Feb 5;7(2):e2355716. doi: 10.1001/jamanetworkopen.2023.55716. PMID: 38349655; PMCID: PMC10865154.
    Link to Article and FULL FREE PDF
  33. Prasanna N, Yamane D, Haridasa N, Davison D, Sparks A, Hawkins K. Safety and efficacy of vasopressor administration through midline catheters. J Crit Care. 2021 Feb;61:1-4. doi: 10.1016/j.jcrc.2020.09.024. Epub 2020 Oct 2. PMID: 33049486.
    Link to (NOT FREE) Article
  34. Link to (NOT FREE) Article
    Link to Article
    Link to FULL FREE PDF
  35. Additional Reading: Articles I did not use.