Selepressin Citations: The Vasopressor & Inotrope Handbook

Lövgren U, Johansson S, Jensen LS, Ekström C, Carlshaf A. Quantitative determination of peptide drug in human plasma samples at low pg/ml levels using coupled column liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal. 2010 Nov 2;53(3):537-45. doi: 10.1016/j.jpba.2010.03.024. Epub 2010 Mar 27. PMID: 20456896.Link to (NOT FREE) Article Rehberg S, Ertmer C, Vincent JL, …

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Vasopressin Citations: The Vasopressor & Inotrope Handbook

Vail EA, Gershengorn HB, Hua M, Walkey AJ, Wunsch H. Epidemiology of Vasopressin Use for Adults with Septic Shock. Ann Am Thorac Soc. 2016 Oct;13(10):1760-1767. doi: 10.1513/AnnalsATS.201604-259OC. PMID: 27404213; PMCID: PMC5122493.Link to ArticleLink to FULL FREE PDF "Vasopressin Injection, USP." FDA.gov, U.S. Food and Drug Administration, 2023.Link to Package Insert Holmes CL, Patel BM, Russell …

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Phenylephrine Citations: The Vasopressor & Inotrope Handbook

Morelli A, Ertmer C, Rehberg S, Lange M, Orecchioni A, Laderchi A, Bachetoni A, D'Alessandro M, Van Aken H, Pietropaoli P, Westphal M. Phenylephrine versus norepinephrine for initial hemodynamic support of patients with septic shock: a randomized, controlled trial. Crit Care. 2008;12(6):R143. doi: 10.1186/cc7121. Epub 2008 Nov 18. PMID: 19017409; PMCID: PMC2646303.Link to ArticleLink to …

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Norepinephrine Citations: The Vasopressor & Inotrope Handbook

Scheeren TWL, Bakker J, De Backer D, Annane D, Asfar P, Boerma EC, Cecconi M, Dubin A, Dünser MW, Duranteau J, Gordon AC, Hamzaoui O, Hernández G, Leone M, Levy B, Martin C, Mebazaa A, Monnet X, Morelli A, Payen D, Pearse R, Pinsky MR, Radermacher P, Reuter D, Saugel B, Sakr Y, Singer M, …

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Terlipressin Citations: The Vasopressor & Inotrope Handbook

Bernadich C, Bandi JC, Melin P, Bosch J. Effects of F-180, a new selective vasoconstrictor peptide, compared with Terlipressin and vasopressin on systemic and splanchnic hemodynamics in a rat model of portal hypertension. Hepatology 1998;27:351–356. DOI: 10.1002/hep.510270206. Link to ArticleLink to FULL FREE PDF Demiselle J, Fage N, Radermacher P, Asfar P. Vasopressin and its analogues …

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phenobarbital alcohol withdrawal

Phenobarbital for Alcohol Withdrawal: Reviewing the Evidence

Have you tried to use phenobarbital for your ICU patients with alcohol withdrawal syndrome?Typically, we use benzodiazepines such as ativan to treat this.Although the empiric data is quite compelling to make the switch.I personally use phenobarbital more often than benzodiazepines these days.The main question of course is the dosing.This single-center, pre-post protocol implementation study is …

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dl vl intubation

Direct (DL) vs Video Laryngoscopy (VL) for Intubation? DEVICE Trial

Your patient needs an airway. What is your go-to tool for endotracheal intubation? Do you reach for direct laryngoscopy (DL) and just get it over with? Or do you wait until the whole setup gets brought into the room to attempt a video laryngoscopy (VL)? The debate of DL vs. VL for intubation has persisted …

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MAP cardiac arrest

MAP (Mean Arterial Pressure) Goal/Target After Cardiac Arrest

Your patient suffered a cardiac arrest and we have achieved ROSC.They are hypotensive and need vasopressors.What MAP should we target in patients after cardiac arrest?The surviving sepsis campaign likes for us to shoot for 65 in septic shock patients.Other studies have shown that patients who are chronically hypertensive could do better with 75.Current guidelines also …

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